Entrepreneurial training programs emerged as strategic interventions for enhancing youth employment and business sustainability, yet their actual impact on long-term business survival remained inadequately documented. In Jinja Municipality, numerous youth entrepreneurship training initiatives were implemented, necessitating systematic assessment of their effectiveness in promoting business sustainability. This study employed a case study research design with a sample of 165 respondents comprising 41 trained youth entrepreneurs, 38 business development trainers and mentors, 71 customers and business associates, and 15 program coordinators and government officials selected through stratified random and purposive sampling techniques. Data were collected using structured questionnaires and interview guides, then analyzed using SPSS version 23. Findings revealed that 73.2% of youth who received entrepreneurial training maintained operational businesses after three years compared to 41.5% of untrained counterparts. Strong positive correlations existed between training quality (r = 0.768), post-training support (r = 0.742), skills application (r = 0.726), and business sustainability. Trained entrepreneurs demonstrated 58.3% higher revenue growth, 64.7% better financial management practices, 52.4% higher innovation rates, and 67.2% greater market competitiveness. Entrepreneurial training significantly enhanced business sustainability through improved business skills, strategic planning capabilities, financial literacy, and entrepreneurial mindset development. The study recommended implementing comprehensive training programs combining technical and soft skills, establishing posttraining mentorship systems, providing access to startup capital, creating business incubation facilities, and developing continuous learning frameworks to enhance youth entrepreneurship sustainability.