The study investigated the influence of financial management practices on the business sustainability of manufacturing firms in Kawempe Division, Kampala Capital City Authority. The study was necessitated by the high rate of business failures among manufacturing firms in the division, which was attributed partly to poor financial management. A cross-sectional survey design was employed, and data were collected from 140 respondents drawn from 47 manufacturing firms. Structured questionnaires and interview guides were the primary data collection instruments. The study examined working capital management, financial planning, and investment management as dimensions of financial management practices. Results showed that working capital management (β=0.341, p