This study investigated the effect of workplace safety on employee productivity at Nansana Municipality in Wakiso District. Specifically, the study was guided by three objectives which included examining the role of physical work environment on employee productivity, the contribution of work safety policies on employee productivity and the how work safety training affects employee productivity at Nansana Municipality. A cross sectional survey utilizing both quantitative and qualitative approach was used. The study targeted 279 participants but 248 managed to respond back. The findings revealed a positive, strong, and significant relationship between the physical work environment and employee productivity (r = .578**, p = 0.00 < 0.01), there was a positive, moderate, and significant relationship between work safety policies and employee productivity (r = .430**, p = 0.00 < 0.01) and results also indicated a positive, moderate, and significant relationship between work safety training and employee productivity (r = .480**, p = 0.00 < 0.01). From regression analysis, it was revealed that the combined constructs of the physical work environment, work safety policies, and work safety training collectively accounted for 39.8% of the variance in employee productivity at Nansana Municipality (Adjusted R Square = .398). Then, the physical work environment positively predicts employee productivity at Nansana Municipality (Beta = .383, p = .000 < 0.05), work safety policies positively predict employee productivity at (Beta = .185, p = .001 < 0.05) and work safety training was also found to positively predict employee productivity at Nansana Municipality (Beta = .217, p = .000 < 0.05). The study recommended that the management of Nansana Municipality should continue investing in the maintenance and improvement of workstations, lighting, ventilation, and office facilities. The management of Nansana Municipality should implement continuous sensitization programs to ensure that all employees are fully aware of safety policies and understand their roles and responsibilities. Lastly, the management of Nansana Municipality should increase the frequency and coverage of safety training sessions to ensure all employees remain up-to-date with workplace safety practices.