The study was about tourism infrastructure development on the tourists’ satisfaction in fort portal city The study was aimed at achieving the following objectives; examine the effects of tourism infrastructure development on tourists’ satisfaction, to examine the effects of cultural image on tourists’ satisfaction and to examine the effects of infrastructure factor on tourists’ satisfaction. The study discovered that despite the importance of infrastructure development on the tourism sector very few papers have tried to explore the relationship of tourism infrastructure development on tourists’ satisfaction in Uganda. This creates the question of what is the impact of infrastructure development on the tourists’ satisfaction in the Ugandan Economy. 36 respondents were selected to give their views about tourism infrastructure and tourist satisfaction and closed ended questionnaire was the main tool used to collect the responses from the different respondents. We used across sectional research design and a quantitative approach. Findings showed that there was a very significant effect between tourism infrastructure and tourist satisfaction; cognitive and tourist satisfaction; and, infrastructure factor and tourist satisfaction. The study therefore, recommends that improvement of tourist satisfaction requires a good tourism having facilities, cognitive images for instance the tourist attractions, accommodation and infrastructure.