The study examined the effect of enforcement and compliance on waste management practices in Kapchorwa municipality markets, Uganda. A mixed-methods approach (qualitative and quantitative) was used. Qualitative approach was used to interview the municipal officials, waste management agencies, and market leaders while quantitative approach was used to survey information from the traders and customers to assess satisfaction with waste services. The study population comprised of 263 market traders/customers in markets and 6 market leaders, municipal officials, and waste management agencies. In this study, the researcher used questionnaire survey and interview guide for the data collection. To test the reliability of the questionnaire as a research instrument, a test-retest technique was employed in which questionnaire was administered to a group of market traders and customers in markets outside Kapchorwa municipality but with similar characteristics. The result of reliability of the questionnaire was established with the use of test-retest reliability with a value of 0.82. validity was determined through face and content validity with a CVI value of 0.76. The findings revealed that there was a moderate positive significant relationship between enforcement and compliance, and waste management practices. It was recommended that enforcement and compliance should continuously improve waste management practices especially in markets since it was found to be moderate predictor, and has a positive relationship with waste management practices in Kapchorwa municipality markets, Uganda.