The study investigates the impact of solid waste disposal on public health in Kisoro Municipality. A total number of three hundred and eighty-four respondents (150) comprising of 60 males and one 90 females were used as a sample of the study respectively for ensuring good coverage. This is in line with Slovenes formula for determining sample size. An instrument developed by the researcher titled the impact of poor solid waste management on public health questionnaire was used for data collection the instrument was validated and reliability index of 0.84 was obtained. The data collected were analyzed using descriptive statistics for research questions Likert scale. The result of the study revealed among others that; poor solid waste disposal lead to outbreak of diseases as the result shows that majority of the respondent were of the view that poor solid waste disposal leads to outbreak of diseases as proof by 50% of the respondents. The study concluded that Proper solid waste disposal should be used to ensure public health safety. The study recommended among others that the community leaders of each ward should be encouraged to enlighten people on the dangers associated with poor solid waste disposal through the public enlightenment to stop dumping of solid waste indiscriminately as this may help to reduce the outbreak of diseases.